Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

* Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily activity of skin and muscles.
* The coordination between the two clocks (central and peripheral) guarantees 50% of the circadian functions of tissues, including vital processes such as the cell cycle, DNA repair, mitochondrial activity, and metabolism.
* Synchronisation between the central brain clock and peripheral ones prevents premature muscle ageing and improves muscle function, suggesting new strategies to tackle age-related decline through circadian rhythm modulation. 

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