A new review highlights the potential of CRISPR-Cas13 for RNA-editing therapies. Discussing the advantages of the effector protein Cas13 over Cas9, they report that CRISPR-Cas13 facilitates RNA knockdown, RNA silencing, RNA splicing, RNA-base editing, and translation regulation. CRISPR-Cas13 has diverse applications like virus detection, antivirus vaccines, and personalized therapies. Additionally, they also discuss the role of AI in enabling the realization of the full potential of RNA-editing technologies.
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