In a first-of-its-kind study, the American Cancer Society (ACS) today released “Cancer in People who Identify as Lesbian, Gay, Bisexual, Transgender, Queer or Gender-nonconforming (LGBTQ+)”. The article provides the latest statistics on the prevalence of cancer screening and modifiable risk factors in LGBTQ+ populations, as well as a review of literature on cancer occurrence and obstacles to cancer prevention and treatment.