Although progress has been made in addressing health disparities and reducing social inequality for lesbian, gay, bisexual, transgender, queer and other sexual or gender minority (LGBTQ+) populations, new challenges have surfaced that harm the health and well-being of those populations, says the American College of Physicians (ACP). A new policy paper published today in Annals of Internal Medicine reaffirms and updates ACP’s policies on LGBTQ+ health.