Children’s Hospital Los Angeles has long been a forceful leader on the issue of medication safety, advising parents on what they can do at home to prevent their kids from ingesting prescription drugs that can do them great harm.Effective medication safety requires adhering to a few simple rules. We break those down here with the guidance of Helen Arbogast, DrPH, MPH, Manager of CHLA’s Injury Prevention Program, and CHLA pediatric surgeon Lorraine Kelley-Quon, MD, MSHS, FACS, FAAP, who oversees the Health Outcomes and Policy Effects (HOPE) Laboratory, which devotes a good portion of its research to studying the risks associated with opioid use for infants, children and adolescents.